Multifratal Analysis of the Pathogenesis of Alzheimer Disease | |
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( Volume 1 Issue 6,December 2015 ) OPEN ACCESS | |
Author(s): | |
Tong-han Lan, Zi-yang Lan, Xiao Li, Hao Cai, Fei fei Yu | |
Abstract: | |
In this paper the fractal analysis method is introduced to characterize the self-similarity of DNA sequences. Using this method, four whole genomes of the pathogenesis of Alzheimer’s Disease provided by NCBI are analyzed. the pathogenesis of Alzheimer’s Disease were exhibited multifractal characteristics when calculating the probability measure for four difference the pathogenesis sequences of each base indidually.From the results we find that Renyi dimension range between 0.0090 to 3.5043. the multifractal characteristic properties in the whole the pathogenesis of Alzheimer’s Disease are verified. The results of this paper suggest that the the multifractal characteristic property is one of the natural properties that DNA sequences possess, and is directly related to the structure and function of the whole DNA molecule. |
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